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Nature 476 (7360), 293297

Melone V, Salvati A, Palumbo D, Giurato G, Nassa G, Rizzo F, Palo L, Giordano A, Incoronato M, Vitale M, et al

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When combined in TUDCA and NAC supplements, these ingredients may support overlapping biological processes such as: Cellular stress response systems Metabolic regulation pathways Bile acid metabolism Antioxidant balance mechanisms For this reason, some manufacturers formulate advanced TUDCA supplements that include NAC alongside bile acids

A.SpinaL.CadoniC.et al (2004)