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However, its important to understand that, in this case, B12 supplementation is secondary to managing diabetes

Recognizing the central role of mitochondria in liver metabolism is crucial for the effective management and treatment of chronic liver diseases [144]

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Elevated levels of reactive oxygen species (ROS) in patients with FM may impair mitochondrial function and energy metabolism in muscle and nerve cells, thereby contributing to chronic, widespread pain [28], while markers of lipid peroxidation have been positively correlated with FM severity scores [29,30]

Since, the standards for glutathione assay and the samples are treated with 4-vinylpyridine at same concentrations and same conditions, the marginal negative effect of 4-vinylpyridine is seen in glutathione standards and samples equally and thus treatment with 4-vinylpyridine does not interfere with estimation of glutathione concentration in the samples