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These medicines include injectable drugs such as semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and exenatide (Byetta, Bydureon), as well as oral semaglutide (Rybelsus)

Going without food can trigger our body's natural defenses against starvation by slowing our metabolism

Patients should also tell surgical and anesthesia teams about GLP-1 or tirzepatide treatment before procedures involving general anesthesia or deep sedation because current labeling includes warnings related to delayed gastric emptying and pulmonary aspiration

Subsequent trials combined both putaminal and SNc injections of neurturin viral transfection to attempt to overcome this limitation 40