Because it stimulates powerful growth pathways in the brain, researchers have flagged several risks and the absence of human trials means its long-term effects are unknown
J.SalterR
When discussing the potential impact of GLP-1 medications on male fertility, emphasize that obesity itself poses a well-established risk to testosterone production and sperm quality
Add margin for priming loss
Findings include changes in satiety signaling, alterations in feeding rhythms, reduced food-seeking behavior, and modulated glucose-response patterns in research subjects
Clin Exp Allergy 47(3):331338 Buldak L, Machnik G, Buldak RJ, Labuzek K, Boldys A, Belowski D et al (2016) Exenatide (a GLP-1 agonist) expresses anti-inflammatory properties in cultured human monocytes/macrophages in a protein kinase A and B/Akt manner