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Efficacy and Safety of Retatrutide, a Novel GLP-1, GIP, and Glucagon Receptor Agonist for Obesity Treatment: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Abdrabou Abouelmagd A

Decreased appetite, mild fatigue, headache

Doctors have long been prescribing Mounjaro and Ozempic off-label for weight loss since their initial FDA approval for use to treat diabetes

That means oral medications spend more time in the stomach and less time in the small intestine where most absorption happens

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The use of these drugs is a trend thats not slowing down. Ramesh is an oculofacial plastic surgeon at the Center for Eye and Facial Plastic Surgery in Somerset, N.J