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Obesity and overweight [OL]

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In contrast, HFD feeding induced marked adipocyte hypertrophy in WT mice, whereas HFD-fed Ssu72 aKO mice exhibited significantly smaller adipocytes and lipid droplets in both eWAT and iWAT (Fig

What it does establish is biological plausibility for restoration: putting back what the body has lost is a more conservative pharmacological proposition than overdriving a healthy system

Small meals on injection day work better, but that is about stomach contents, not medication absorption