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This protective effect appeared to be mediated through up-regulation of neurotrophic factor-1 (NF-1) and subsequent enhancement of fibroblast growth factor-2 (FGF2) expression and hippocampal neurogenesis
(4) Baar MP, Brandt RMC, Putavet DA, Klein JDD, Derks KWJ, Bourgeois BRM, Stryeck S, Rijksen Y, van Willigenburg H, Feijtel DA, van der Pluijm I, Essers J, van Cappellen WA, van IJcken WF, Houtsmuller AB, Pothof J, de Bruin RWF, Madl T, Hoeijmakers JHJ, Campisi J, de Keizer PLJ
[PubMed] Brustolin, S., Giugliani, R., & Flix, T
Consequently, with this, patients feel minimal pain in the injection area