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2021 Feb;121(2):621-635 Foued Ftaiti F

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doi: 10.1111/febs.15195 62 YoshidaHMatsuiTYamamotoAOkadaTMoriK

In A Study of Olezarsen Administered to Patients With Familial Chylomicronemia Syndrome (BALANCE), 66 patients with genetically confirmed FCS (homozygous or heterozygous compound loss function mutations in the genes for LPL, apoC2, apoA5, LMF-1 , or GPIHBP1 ) and fasting TG 880 mg/dl ( 10 mmol/l) were randomized to receive placebo or olezarsen at 50 or 80 mg monthly [106]

GHK-Cu's clinical dataset is smaller but contains some results worth noting