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The review authors noted that research into the potential brain benefits of GLP-1 medications needs more research but are optimistic about the future of these drugs in how they may boost brain health

[7] All potential female patients are screened and counseled on this point, and effective contraception is recommended for those undergoing NAD+ therapy if applicable

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The point is this: even if both semaglutide and tirzepatide fail, the medication pipeline contains multiple next-generation options targeting different receptor combinations