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Gross necropsy and histopathologic examination of animals receiving high-dose BPC-157 found no organ damage in liver, spleen, lung, kidney, brain, thymus, prostate, ovaries, or gastric wall

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Its high selectivity and confirmed membrane permeability make it one of the most reliable small-molecule tools currently available for interrogating the NNMT pathway in both cell-based and in vivo experimental models

Also, the evidence demonstrates modulatory effects of BPC 157 on vasomotor tone and the activation of the Src-Caveolin-1-endothelial NOS pathway [93]