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Excessive mitochondrial fission is believed to enhance fibroblast proliferation and collagen production, likely because mitochondrial fission acts downstream of TGF-1 [74]
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Interestingly, intradiscal MSC injection increased the number of NCs and matrix deposition in murine degenerated IVDs [30]
It is, however, well worth investigating the orobuccal absorption of glutathione in view of what we prefer to call intestinal inflation in that over 90% of it is destroyed and eliminated in the gastrointestinal tract
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