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Such a review is essential to consolidate current knowledge, resolve outstanding controversies, and define priorities for translating ferroptosis biology into cardiovascular medicine

In addition to losing elasticity, skin also naturally begins to lose collagen, a protein that gives skin its structure, support, and strength

Diagnosis can be further confirmed by demonstrating reduced carnitine transport in skin fibroblasts in the patient or by mutation analyses of the SLC22A5 gene

Statistical analysis was carried out with a Students t-test in Origin 9.0 (Originlab, USA)