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Contrave uses a dual-mechanism approach to weight loss, combining two medications that target different pathways in the brain

If you're prone to bloating, be cautious with: Inulin, chicory root, FOS (fructooligosaccharides), and large amounts of GOS (galactooligosaccharides) Sugar alcohols (sorbitol, mannitol, xylitol) "Proprietary blends" that hide amounts If you do well on a low FODMAP diet (often used for IBS management), you may prefer a probiotic without heavy prebiotic fibers, at least during GLP-1 dose escalation

In this Review, we provide an overview of dopamine metabolism and signalling pathways in the central nervous system and periphery and their effects on gastrointestinal health and disease

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Holst JJ, Madsbad S, Bojsen-Mller KN, et al