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It believed that in physiologic conditions when the membrane transporters are saturated, the leak pathway complements the transcellular pathway (active transport) in absorbing water and nutrients (13)
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Colsoul B, Schraenen A, Lemaire K et al (2010) Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice
Vitamin D, in particular, is well-known for its role in regulating skin cell growth
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