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Ruff CT, Baron M, Im K, ODonoghue ML, Fiedorek FT, Sabatine MS

JAMA 2024

A study published in PMC examining chemical intolerance and mast cell activation found that alterations in the redox system, glutathione depletion, and pro-inflammatory cytokines interact to affect mast cell behavior. 13 When glutathione is depleted, oxidative stress increases, which can trigger mast cell activation through multiple pathways

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