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AEDG peptide (Epitalon) stimulates gene expression and protein synthesis during neurogenesis: Possible epigenetic mechanism

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Signalling activates PLC- DAG + IP3 intracellular Ca + PKC (via Gq) plus Gs-cAMP-PKA, with a balanced profile neither Gs- nor -arrestin-biased in recent cryo-EM and BRET studies (2020-2023)