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FIGURE 8 FIGURE 9 Conclusion By using the GPX4 activator compound as chemical probe, we demonstrated that up-regulation of GPX4 activity can reduce the production of inflammatory agents and promote inflammation resolution ( Figure 10 )

doi: 10.1056/NEJMoa1603827 38 MarsoSPBainSCConsoliAEliaschewitzFGJdarELeiterLAet al