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This change in the body contributes to cardionomic imbalance for which palpitation is a symptom

In glycemic control trials with semaglutide injection, acute pancreatitis was reported in 7 semaglutide-treated patients (0.3 cases per 100 patient-years) versus 3 in comparator-treated patients (0.2 cases per 100 patient-years)

Injections require sterile technique to prevent infection, which is easier to ensure under a doctors supervision