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For T2DM, clinical studies confirm that DSS not only improves glycemic control but also alleviates specific complications, including diabetic neuropathy and nephropathy, suggesting a systemic protective effect beyond mere glucose-lowering (Xiao-bin, 2019

10.1021/tx5000443 32 JenkinsR

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They're contraindicated in anyone with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 [3][4]

The most commonly reported side effects involve the gastrointestinal system, such as nausea, vomiting, and diarrheaeffects that typically diminish after the first few weeks of treatment