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Randomised, controlled trial of N-acetylcysteine for treatment of acute exacerbations of chronic obstructive pulmonary disease [ISRCTN21676344]
A systematic evaluation of time- and dose-dependent effects has been provided by Shihana et al., highlighting the importance of protocol optimization for reproducible pharmacological screening (Shihana et al., 2023)
If there is a link between this increase in melatonin production and the efficacy of antidepressant medications this needs further evaluation
The obtained data suggest the accelerated accumulation of intraparenchymal glutamate after ischemia, which was even more pronounced in the preconditioned animals three days after an ischemic event
An IL-23/Th17 axis positive feedback loop is established when activated Th17 cells enhance the inflammatory response
Estimating the remaining G6PD enzyme activity is the most direct, accessible, and reliable assessment of the phenotype and remains the gold standard for the diagnosis of patients who could be harmed by the administration of primaquine
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