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GLP-1RA may influence the activity of two opposite subgroup neurons within ARC, which are related to food intake and body weight, containing proopiomelanocortin/cocaine- and amphetamine-regulated transcript (POMC/CART) and neuropeptide Y/agouti related peptide (NPY/AgRP) neurons

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M., Huang, H., Lee, H

However, some patients find that eating a light meal 12 hours before injection reduces lightheadedness or injection-site discomfort

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