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Accumulation of misfolded, abnormally modified protein and impaired protein homeostasis are common disease mechanisms in many neurodegenerative disorders, including PD 92,93

169,174 Moreover, delayed absorption of the concomitant drug due to delayed gastric emptying can be minimized by administering the drug 1 h before GLP-1 RAs or a dual GLP-1/GIP RA administration

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