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While animal studies have shown promising results for tissue repair and anti-inflammatory effects, large-scale randomized controlled trials in humans are lacking

Low Plasma Ergothioneine Predicts Cognitive and Functional Decline in an Elderly Cohort Attending Memory Clinics

Supplementation of dietary copper has been reported to reduce the severity of osteochondrosis and other developmental cartilage lesions, which may result from enhanced collagen cross-linking and increased collagen II synthesis (Knight et al., 1990

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Thus, cell survival is largely dependent on sustained physiological levels of NO [22]

Commun Biol 8 , 15 (2025)