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& Chappard, D

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By contrast, long-acting GLP-1RAs lower fasting blood glucose and hemoglobin A1c (HbA1c) by stimulating insulin secretion [35]

JAMA 314 , 687699 (2015)

administration and observed a half-life of 1.9 h for GLP-1MK-801, which is longer than the parent GLP-1 analogue, but comparable to that of the GLP-1inactive MK-801 conjugate (Fig

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