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Paraxanthine, a less-studied CAF metabolite, has distinct pharmacokinetic and pharmacodynamic properties [6, 12] increasing dopaminergic activity [22] and potentially improving memory consolidation more effectively than caffeine

The H-ESI source was operated in positive mode at spray voltage 3,500 or negative mode at spray voltage 2,500 with the following parameters: sheath gas 35 a.u., aux gas 7 a.u., sweep gas 0 a.u., ion transfer tube temperature 320 C, vaporizer temperature 275 C, mass range 70 to 1,000 m/z , full scan MS1 mass resolution of 120,000 FWHM, RF lens at 70% and standard AGC

American Society of Health-System Pharmacists (ASHP)