Sauce D, Dong Y, Campillo-Gimenez L, Casulli S, Bayard C, Autran B, et al
10.1164/rccm.201303-0427OC Am J Respir Crit Care Med
Copper Chelation and Delivery At the most fundamental level, GHK functions as a copper chelator and delivery system - the tripeptide binds Cu with exceptionally high affinity (binding constant approximately 10 M, among the highest known for biological copper chelators), forming a square planar coordination complex where the copper ion is coordinated by the nitrogen atoms of the terminal amino group, the two peptide bonds, and the imidazole nitrogen of histidine
However, this comes at the cost of much lower effectiveness
Kunal Shah, clinical director of obesity medicine at the Rutgers Center for Metabolic Health and Weight Management
The program is also a better conceptual fit if you want food, sleep, exercise, and emotional-health curriculum alongside medication