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Kaczmarzyk et al

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5 Adipose tissue contributes to systemic inflammation through the secretion of proinflammatory cytokines such as tumor necrosis factor (TNF) and interleukins (ILs)

1 Introduction Coronary heart disease (CHD) represents a significant threat to global health, characterized by complex and multifactorial pathogenesis ( The pathophysiological significance of ferroptosis in cardiovascular disease stems from its multifaceted involvement in abnormal iron metabolism, lipid peroxidation, and ROS accumulationprocesses fundamental to the development of coronary artery disease (CAD)

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