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Semaglutide downregulates PPARG, modifying lipid metabolism within macrophages

In its first year, 8.4 million prescriptions were written for the drug, and it garnered a record $582.7 million in sales

Formulated in the USA, non-GMO, and third-party tested

Using a translational rodent model of concussion/mild traumatic brain injury (mTBI), the effects of voluntary exercise on were investigated, assessing post-concussive syndrome (PCS) and gene (bdnf, dnmt1, Igf-1, pgc1-a, Tert) expression changes in the prefrontal cortex and hippocampus

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doi: 10.1016/j.redox.2020.101544 123 NumakuraTSugiuraHAkaikeTIdaTFujiiSKoaraiAet al