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Moreover, the placebo group had 136 detected genes, whereas in the probiotic group 129 genes were detected

(PubMed) Gibellini F, Smith TK

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The complementary mechanisms also mean that side effects are generally not additive, though gastrointestinal symptoms may occur with both medications and require careful management during the initiation phase

Since collagen forms the organic matrix of bone, providing the framework onto which mineral crystals are deposited, enhanced collagen production directly supports bone formation