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Developed initially by NeuroSearch for treatment of Alzheimer's and Parkinson's diseases, tesofensine was repurposed for obesity management after clinical trials consistently revealed substantial weight loss as a prominent effect in participants

This might involve daily use for a set period (such as 3 to 6 months) followed by a reassessment

Demonstrates that NNMT activity regulates adipogenesis and energy expenditure in murine models, establishing NNMT as a key metabolic enzyme target

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If blood work confirms this to be the case, conception without assistance can be more difficult

10.1111/joim.12785 195 MahdiA.PernowJ.KovameesO