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A significant finding is its effect in pathological scarring models, such as keloids, where it promoted apoptosis in resistant fibroblasts and reduced cell proliferation during the G0/G1 phase of the cell cycle

Similarly, SGLT2 inhibitors have demonstrated robust cardiovascular and renal benefits, including reductions in cardiovascular events and all-cause mortality, with consistent effects across the drug class and irrespective of diabetes status [6, 7] Their metabolic benefitssuch as weight loss, improved lipid profiles, and reduced visceral adipositycontribute to a favourable cardiovascular risk profile, countering the pro-atherogenic state typical of T2DM [8]

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doi: 10.1016/j.lfs.2006.09.018

Tissue engineering is one discipline which has been explored to counteract these problems

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