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In the absence of coenzyme B12, tetrahydrofolate cannot be regenerated from its inactive storage form, 5-methyltetrahydrofolate, and a functional folate deficiency occurs

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According to Durkin, several committee members appeared to view FDAs assessment as applying an overly restrictive standard for evaluating compounded peptides, while FDA scientists emphasized the limited clinical evidence supporting many of the substances

When that data is missing, humility is warranted

That research has not yet progressed to randomized, controlled human clinical trials for any indication a distinction that applies across the entire BPC-157 product category, not just to ProHealth's formulation