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Subcutaneous: What's the Difference

At the same dose, a 74 kg participant had about 1.4 times the exposure of a 110 kg reference, while a 143 kg participant had about 0.8 times. Weight alone does not set the dose, but it helps explain why the trial mean transfers poorly to bodies outside the studied range

Results were expressed in nmol per mg protein

Improvement is real but builds week over week rather than appearing as a sudden change

Too little, and its overly concentrated, increasing the risk of error

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