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Your healthcare provider will need to assess whether you meet the criteria for GLP-1 receptor agonist therapy, which typically includes having type 2 diabetes with inadequate control on metformin alone (HbA1c above target) according to NICE guideline NG28

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Mechanistic studies provide some evidence supporting the immunomodulatory capacity of GLP-1 RAs, showing reductions in key proinflammatory cytokines such as IL-17 and dermal T-cell infiltration in psoriatic lesions

patients complete an online assessment, connect with a provider, and receive prescriptions shipped directly

TRIUMPH-1, the pivotal obesity trial, reported on May 21, 2026 , and TRIUMPH-2 (obesity in type 2 diabetes) and TRIUMPH-3 (obesity with established cardiovascular disease) both reported on July 23, 2026 so the core evidence package for this filing is in hand

Brand-name tirzepatide costs approximately $1,400-$1,600 per month