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Only the 4mg group flattens out at the end of the trial

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N Engl J Med (2012) 366(17):156776.10.1056/NEJMoa1200225 14 IkramuddinSKornerJLeeWJConnettJEInabnetWBBillingtonCJet alRoux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial

The right approach focuses on steady fat loss while protecting muscle and metabolic health