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Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice
Epub 2013 Jun 9
Newer oral forms, liposomal ones for instance, absorb better, but intravenous delivery still offers the highest bioavailability, because practically the whole dose reaches the blood
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Fourth, (5) (4.0 g, 10.4 mmol) was mixed with CH 2 Cl 2 (30 mL), and (2) (2.2 g, 12.5 mmol), 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDCHCl) (2.8 g, 14.6 mmol), 4-(dimethylamino)pyridine (DMAP) (1.5 g, 12.5 mmol), and triethylamine (Et 3 N) (2.9 mL, 20.8 mmol) were added into the (5) mixture under vigorous stirring at room temperature