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The copper-binding property is not incidental

doi: 10.1016/j.jep.2023.117089 96 ChyauC-CWangH-FZhangW-JChenC-CHuangS-HChangC-Cet al

Tolerance is a physiological state characterized by a reduced response to a drug after repeated administration (i.e., a higher dose of a drug is required to produce the same effect that was once obtained at a lower dose)

Abstract Colorectal cancer (CRC) chemotherapy remains clinically challenging due to the emergence of drug resistance, off-target toxicity, and suboptimal patient compliance, underscoring the need for innovative, patient-centric delivery systems specially designed for targeted CRC therapy

But oral supplements only deliver about 20% absorption due to digestive breakdown

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