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Malaguarnera, M., Vacante, M., Giordano, M., Motta, M., Bertino, G., Pennisi, M., Neri, S., Malaguarnera, M., Li, Volti G., and Galvano, F

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Betaine is converted to TMA through the action of betaine reductase

2 Research continuity Preclinical studies administered compound over 412 week observation periods

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133 In an animal model, dietary supplementation with selenium was associated with low levels of cardiac oxidative damage and increased antioxidant expression, as well as a reduction in disease severity and mortality in spontaneously hypertensive rats