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In addition to characterizing a new family of HGF/Met antagonists, this Example demonstrates a qualitative relationship between the ability of a compound to bind HGF and block HGF dimerization and its observed in vitro biological activity

Animals are tested in glass cylinder, where they adapt for 10 minutes prior to assessment

Most patients can drive after upper extremity injections without assistance

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Treatment Duration: Standard cycles run for 10-20 days

Whether after rotator cuff repair, labral repair, or shoulder replacement, the post-operative healing period is critical