Microbial dysbiosis leads to an increase in opportunistic pathogens and a reduction in beneficial bacteria, which collectively result in the excessive production of detrimental metabolites, particularly uremic toxins such as indoxyl sulfate and trimethylamine-N-oxide, while concurrently decreasing beneficial metabolites, such as short-chain fatty acids and tryptophan catabolites, including indole-3-aldehyde
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As described above, GSTM2 modulated the size of LDs
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doi: 10.1186/s12958-024-01273-z
It consists of the tripeptide glycyl-L-histidyl-L-lysine complexed with a divalent copper ion, forming a high-affinity chelate that facilitates controlled copper delivery within biological systems
