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PMC12852416 (2025) 6

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Golimumab also demonstrated reduced radiographic progression relative to placebo in this study

Steroid-genic factor-1 (SF-1) transcription factor is upregulated in the process of granulosa-cell differentiation and luteinization, which in turn suggests that SF-1 is essential to the process of specification of granulosa-cell into luteal cells (57)

Astrocytes possess a greater concentration of glutathione (3,8 mmol/L) than neurons (2.5 mmol), probably due to a higher content of the astrocytic enzyme y-glutamylcysteine synthethase (EC 6.3.2.2) [6]

This protein is normally located in the cytosol