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[109] Figure Structures of Rosiglitazone and Pioglitazone The primary effects of pioglitazone (Figure 1.7) and rosiglitazone (Figure 1.8) are the reduction of insulin resistance and improvement of insulin sensitivity, resulting in a reduction of fasting plasma glucose, insulin, and free fatty acids [110][111][112][113][114]

Knowing you need approximately one 10mg vial every 1.25 weeks at the 8mg dose means you need roughly 3.5 vials for a four-week maintenance block

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Microdosing starts at doses below the lowest commercially available starting dose and is titrated slowly to achieve neuromodulatory and metabolic effects without the full appetite suppression or side effects of standard dosing