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Muller, P

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Interestingly, the methylation reactions are catalyzed by enzymes requiring vitamin B12 and folate as co-factors

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As these decline with age, the skins ability to snap back diminishes

GHK-Cu was discovered in 1973 and has been found to stimulate dermal fibroblasts in the dermis and upregulate the production of collagen, elastin, and glycosaminoglycanthe main components of the intercellular matrix of tissues such as the skin [4]