One such mechanism, which provides immune privilege and prevents NK-cell-mediated cytotoxicity, is the intracellular localization within melanoma cells of the ligand that typically activates NKD2D receptors on NK-cells [31]
Collagen and Matrix Support: Stimulates synthesis of collagen types I and III, elastin, proteoglycans, and glycosaminoglycans
(See the green area in Figure AM) Do not inject into your belly button, nor on areas with scar tissue, bruises or on any hard bumps from previous injections
Improper Storage: Leaving a reconstituted vial at room temperature or exposed to direct sunlight is a surefire way to degrade the peptide
J Neuroimmunol (2014) 274(1-2):5361
If that inflammatory response is excessive, or if the skin is pushed too aggressively in a single session, the melanocytes respond by producing excess pigment