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Have serious or unstable medical conditions without close medical supervision

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The STEP 1 trial (N=1,961) published in the New England Journal of Medicine in 2021 (DOI: 10.1056/NEJMoa2032183) demonstrated 14.9% mean body weight reduction with semaglutide 2.4mg weekly versus 2.4% with placebo over 68 weeks

5 Translational bottlenecks from the laboratory to the clinic Probiotic supplementation in patients with systemic lupus erythematosus (SLE) shows promising potential benefits but also requires careful consideration of safety

Its ability to cross the blood-brain barrier further supports its role in modulating brain activity

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