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In December 2025, Winfrey told People that she went off the medication for a year because she wanted to prove that she could "do without it," but ended up gaining 20 pounds

Polyphenol Epigallocatechin-3-Gallate Epigallocatechin-3-gallate (EGCG, Figure 4A) belongs to catechin polyphenols and is one of the main bioactive substances in Camellia sinensis (L.) Kuntze (Huang et al., 2021)

Saudi J Kidney Dis Transpl 22:11551159 Derosa G, Maffioli P, Ferrari I, DAngelo A, Fogari E, Palumbo I, Randazzo S, Cicero AF (2010) Orlistat and l-carnitine compared to orlistat alone on insulin resistance in obese diabetic patients