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Cracked corners of the mouth Vitamin B deficiencies, especially vitamins B2 and B3, have been linked to cracked corners of the mouth and other symptoms such as dry skin, a red tongue, and a swollen mouth

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An analysis of 26 studies (total 3020 patients) including 5 studies with psychiatric symptoms assessed as primary outcomes (for example, substance use disorders), and 21 studies with secondary outcomes, as well as an additional 10 registered clinical studies, was performed