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Studies have shown that a significant proportion of patients experience weight regain after stopping GLP-1 RA therapy, with some regaining up to two-thirds of their lost weight within a year of discontinuation

Despite their broad spectrum of antioxidant, anti-inflammatory, neuroprotective, antimicrobial, anti-diabetic, and anti-cancer activities, the therapeutic application of polyphenols is significantly hindered by their inherently poor bioavailability