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Both are studied in relation to growth hormone release, but via different receptors Tesamorelin acts on GHRH receptors, while Ipamorelin acts through the ghrelin receptor pathway

Tesamorelin is FDA-approved as Egrifta for visceral fat reduction in HIV lipodystrophy, and Sermorelin held a past FDA approval before being discontinued for business reasons

Muscle pain and body aches Muscle pain and general body aches occur in some patients, particularly during early treatment or after dose escalation

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