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Similar therapeutic effects were also observed on Huh7 xenografts, where BAY-876SU056 combination treatment dramatically dampened tumor growth (Extended Data Fig

FOXO4-DRI is studied in preclinical longevity models to evaluate how senescent cell clearance influences biological aging markers

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Evidence limits: Human evidence is limited to small Russian trials using the intranasal spray

Mol Metab (2013) 2:14252.10.1016/j.molmet.2013.03.001 58 OrskovCPoulsenSSMollerMHolstJJ

Traditional growth hormone therapy carries risks including fluid retention, joint pain (paradoxically), carpal tunnel syndrome, and increased cancer risk